Prof. Sahu is a well known surgeon of ano-rectal diseases having expertise in Chhar Sutra technique. Presently Prof. Sahu is Coordinator of National Resource Centre for Chhar Sutra. He joined Ayurveda Faculty as Reader in 1993 and served the Shalya Tantra as head on 3 occasions.

Prof. Manoranjan Sahu, Faculty of Ayurveda of Institute of Medical Sciences, Banaras Hindu University, has been served as Director of All India Institute of Ayurveda, New Delhi by the Ministry of Health and Family Welfare (Department of AYUSH), Govt. of India.

Prof. Sahu has also worked as Professor In-charge of Ayurveda wing of Sir Sundarlal Hospital of BHU. Prof. Sahu has the credit of publishing more than 35 research papers at international level. He has visited countries like France, South Korea, Vietnam, Srilanaka and Thailand for participating in international seminars to deliver lectures.